Bis(2-chlorophenyl)methanol → Carbonic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester bis-(2-chloro-phenyl)-methyl ester

HRID 1664640

반응식

HRID 1664640 반응식
[N:1]12[CH2:8][CH2:7][CH:4]([CH2:5][CH2:6]1)[C@@H:3]([O:9][C:10](N1C=CN=C1)=[O:11])[CH2:2]2.[Cl:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[CH:24]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=1[Cl:32])[OH:25]>>[Cl:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[CH:24]([O:25][C:10](=[O:11])[O:9][C@@H:3]1[CH:4]2[CH2:5][CH2:6][N:1]([CH2:8][CH2:7]2)[CH2:2]1)[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=1[Cl:32]

참가 물질

3

반응물 2

HCID 230561Bis(2-chlorophenyl)methanolHCID 59187189imidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl ester

생성물 1

HCID 66626915Carbonic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester bis-(2-chloro-phenyl)-methyl ester

실험 절차

The desired product was prepared by reacting imidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl ester with bis(2-chlorophenyl)methanol.

출처 및 근거

ORD 기록
ord-d368b93959f7477cbe0b281db5680974
출처 데이터셋
uspto-grants-2011_10
특허 번호
US08039483B2

연결된 노트

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