Trifluoroacetic acid → 1-Piperidin-4-ylimidazolidine-2,4-dione
반응식
FC(F)(F)C(O)=O.[O:8]=[C:9]1[NH:13][C:12](=[O:14])[CH2:11][N:10]1[CH:15]1[CH2:20][CH2:19][N:18](C(OC(C)(C)C)=O)[CH2:17][CH2:16]1>ClCCl>[NH:18]1[CH2:17][CH2:16][CH:15]([N:10]2[CH2:11][C:12](=[O:14])[NH:13][C:9]2=[O:8])[CH2:20][CH2:19]1참가 물질
4
실험 절차
Trifluoroacetic acid (0.300 mL) was added to a solution of tert-butyl 4-(2,4-dioxoimidazolidin-1-yl)piperidine-1-carboxylate (32 mg, 0.113 mmol) in dichloromethane (1 mL). After 4 h, the reaction was concentrated to give the title compound. MS 184.04 (M+1).
후처리
- concentrationthe reaction was concentrated
출처 및 근거
- ORD 기록
- ord-b8489b22351c424ab96b27b0202d54f6
- 출처 데이터셋
- uspto-grants-2011_10
- 특허 번호
- US08039460B2
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