4-(2,4-Dichlorobenzoyl)piperidine → HCID 178453900, 화합물

반응식

[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]([CH:11]1[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]1)=[O:10].[C:17]([O:21][C:22](=[O:33])[NH:23][C@H:24]1[CH2:29][CH2:28][C@H:27]([CH2:30][CH:31]=O)[CH2:26][CH2:25]1)([CH3:20])([CH3:19])[CH3:18]>>[C:17]([O:21][C:22](=[O:33])[NH:23][C@H:24]1[CH2:25][CH2:26][C@H:27]([CH2:30][CH2:31][N:14]2[CH2:15][CH2:16][CH:11]([C:9](=[O:10])[C:3]3[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=3[Cl:1])[CH2:12][CH2:13]2)[CH2:28][CH2:29]1)([CH3:20])([CH3:19])[CH3:18]

참가 물질

반응물 2

HCID 130763944-(2,4-Dichlorobenzoyl)piperidine

HCID 178453924HCID 178453924, 화합물

생성물 1

HCID 178453900HCID 178453900, 화합물

실험 절차

The title compound was prepared as described on example 1 from (2,4-Dichloro-phenyl)-piperidin-4-yl-methanone and Trans-[4-(2-Oxo-ethyl)-cyclohexyl]-carbamic acid tert-butylester (m/e): 483.4 (M+H+)

출처 및 근거

ORD 기록: ord-5ee012dbe2624446b052d4b5b077b59a
출처 데이터셋: uspto-grants-2011_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08039490B2

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