Trifluoroacetic acid → HCID 178511514, 화합물

반응식

C(OC(=O)[NH:7][C@H:8]1[CH2:13][CH2:12][C@H:11]([CH2:14][CH2:15][N:16]2[CH2:21][CH2:20][CH:19]([C:22](=[O:31])[C:23]3[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][C:24]=3[Cl:30])[CH2:18][CH2:17]2)[CH2:10][CH2:9]1)(C)(C)C.FC(F)(F)C(O)=O>>[NH2:7][C@H:8]1[CH2:13][CH2:12][C@H:11]([CH2:14][CH2:15][N:16]2[CH2:17][CH2:18][CH:19]([C:22]([C:23]3[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][C:24]=3[Cl:30])=[O:31])[CH2:20][CH2:21]2)[CH2:10][CH2:9]1

참가 물질

반응물 2

HCID 6422Trifluoroacetic acid

HCID 178453900HCID 178453900, 화합물

생성물 1

HCID 178511514HCID 178511514, 화합물

실험 절차

The title compound was prepared as described on example 1 from Trans (4-{2-[4-(2,4-Dichloro-benzoyl)-piperidin-1-yl]-ethyl}-cyclohexyl)-carbamic acid tert-butyl ester and trifluoroacetic acid (m/e): 383.3 (M+H+).

출처 및 근거

ORD 기록: ord-a56448d034e744439375e3f688c72e3f
출처 데이터셋: uspto-grants-2011_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08039490B2

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