Piperidin-4-yl(thiophen-2-yl)methanone hydrochloride → HCID 178474968, 화합물

HRID 1664991노트

반응식

HRID 1664991 반응식
Cl.[NH:2]1[CH2:7][CH2:6][CH:5]([C:8]([C:10]2[S:11][CH:12]=[CH:13][CH:14]=2)=[O:9])[CH2:4][CH2:3]1.O=[CH:16][CH2:17][C@H:18]1[CH2:23][CH2:22][C@H:21]([NH:24][C:25](=[O:27])[CH3:26])[CH2:20][CH2:19]1>>[S:11]1[CH:12]=[CH:13][CH:14]=[C:10]1[C:8]([CH:5]1[CH2:6][CH2:7][N:2]([CH2:16][CH2:17][C@H:18]2[CH2:23][CH2:22][C@H:21]([NH:24][C:25](=[O:27])[CH3:26])[CH2:20][CH2:19]2)[CH2:3][CH2:4]1)=[O:9]

참가 물질

3

반응물 2

HCID 18525948Piperidin-4-yl(thiophen-2-yl)methanone hydrochlorideHCID 178474986HCID 178474986, 화합물

생성물 1

HCID 178474968HCID 178474968, 화합물

실험 절차

From piperidin-4-yl-thiophen-2-yl-methanone hydrochloride (74 mg) and N-[trans-4-(2-oxo-ethyl)-cyclohexyl]-acetamide (64 mg, intermediate AG). Yield: 75 mg (65%). Light yellow solid. MS (m/z): 363.4 ([M+H]+).

출처 및 근거

ORD 기록
ord-653b36bdb9024b94b1c3902bf96146bb
출처 데이터셋
uspto-grants-2011_10
특허 번호
US08039490B2

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