Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Chlorobenzenesulphonyl chloride → N-(5-bromo-thiophen-2-ylmethyl)-3-chloro-benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Chlorobenzenesulphonyl chloride | HCID 17909 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | (5-Bromothiophen-2-yl)methanamine | HCID 23130577 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-(5-bromo-thiophen-2-ylmethyl)-3-chloro-benzenesulfonamide | HCID 35408893 | — |
반응 단계
In analogy to example 4, step 1, 1-(5-bromo-2-thienyl)methanamine was reacted with 3-chlorobenzenesulfonyl chloride and N,N-diisopropyl ethyl amine in dichloromethane to give N-(5-bromo-thiophen-2-ylmethyl)-3-chloro-benzenesulfonamide as a colorless solid. MS: 363.9 ([M−H]−)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08039493B2 |
| 출처 데이터셋 | uspto-grants-2011_10 |
| ORD ID | ord-56badee85d834d08b71575581cd23efe |
| 출처 메모 | uspto-grants-2011_10 |