Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Hydroxide → 3-(2',4',5'-Trifluoro-biphenyl-4-yloxymethyl)-benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 3-(2',4',5'-Trifluoro-biphenyl-4-yloxymethyl)-benzoic acid methyl ester | HCID 67150368 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-(2',4',5'-Trifluoro-biphenyl-4-yloxymethyl)-benzoic acid | HCID 58271190 | 93.2% |
반응 단계
3-(2′,4′,5′-Trifluoro-biphenyl-4-yloxymethyl)-benzoic acid methyl ester (2.9 g, 7.79 mmol) and 2N KOH (15.6 mL, 31.2 mmol) in 140 mL MeOH were reacted as above to yield 2.6 g (93.2%) of 3-(2′,4′,5′-trifluoro-biphenyl-4-yloxymethyl)-benzoic acid. LC-MS (ES) calculated for C20H13F3O3, 358.32; found m/z 357.1 [M−H]−.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08039495B2 |
| 출처 데이터셋 | uspto-grants-2011_10 |
| ORD ID | ord-609658ca5e9d4318a596d2c7c9fcae05 |
| 출처 메모 | uspto-grants-2011_10 |