2-Methyl-2-vinyloxirane → HCID 57661848, 화합물

HRID 1665356

반응식

HRID 1665356 반응식
[NH:1]1[CH2:6][CH2:5][C:4]2([O:11][C:10]3[C:12]4[C:17]([C:18](=[O:21])[C:19](=[O:20])[C:9]=3[S:8][CH2:7]2)=[CH:16][CH:15]=[CH:14][CH:13]=4)[CH2:3][CH2:2]1.[CH3:22][C:23]1([CH:26]=[CH2:27])[CH2:25][O:24]1>>[OH:24][C:23]([CH3:25])([CH:26]=[CH2:27])[CH2:22][N:1]1[CH2:2][CH2:3][C:4]2([O:11][C:10]3[C:12]4[C:17]([C:18](=[O:21])[C:19](=[O:20])[C:9]=3[S:8][CH2:7]2)=[CH:16][CH:15]=[CH:14][CH:13]=4)[CH2:5][CH2:6]1

참가 물질

3

반응물 2

HCID 921662-Methyl-2-vinyloxiraneHCID 57661820Spiro[naphtho[1,2-b][1,4]oxathiine-2,4'-piperidine]-5,6-dione

생성물 1

HCID 57661848HCID 57661848, 화합물

실험 절차

Compound 159 was synthesized using spiro[naphtho[1,2-b][1,4]oxathiine-2,4′-piperidine]-5,6-dione, 2-methyl-2-vinyloxirane and conditions outlined in procedure X. M.p.=74-77° C.; 400 MHz 1H NMR (CDCl3) δ: 8.05 (d, 1H), 7.75 (d, 1H), 7.65 (t, 1H), 7.5 (t, 1H), 5.9 (dd, 1H), 5.35 (d, 1H), 5.05 (d, 1H), 3.0-2.7 (m, 4H), 2.6 (m, 4H), 2.45 (d, 1H), 2.1 (t, 2H), 1.9-1.75 (m, 2H), 1.2 (s, 3H); LCMS: 386 [M+H].

출처 및 근거

ORD 기록
ord-37224cd2fa544cbea303d79c0546dba0
출처 데이터셋
uspto-grants-2011_10
특허 번호
US08039503B2

연결된 노트

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