4-nitro-1-phenyl-1H-pyrazole → 1-Phenyl-1H-pyrazol-4-amine
반응식
[N+:1]([C:4]1[CH:5]=[N:6][N:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:8]=1)([O-])=O>CO.CCOC(C)=O.[Pd]>[NH2:1][C:4]1[CH:5]=[N:6][N:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:8]=1참가 물질
5
실험 절차
10% Pd/C (25 mg) was added to a stirred solution of 4-nitro-1-phenyl-1H-pyrazole (240 mg, 1.2 mmol) in a mixture of MeOH (2.5 mL) and EtOAc (2.5 mL) and stirred under H2 atmosphere overnight. The reaction mixture was filtered through celite and the filtrate so obtained was concentrated under reduced pressure to afford 140 mg (69365% Yield) of 4-amino-1-phenyl-1H-pyrazole.
후처리
- filtrationThe reaction mixture was filtered through celite
- customthe filtrate so obtained
- concentrationwas concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-345f202434ea4f7fbb743edc229a4c99
- 출처 데이터셋
- uspto-grants-2011_10
- 특허 번호
- US08039463B2
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