Trifluoroacetic acid → HCID 66875752, 화합물

HRID 1666514노트

반응식

HRID 1666514 반응식
C(OC([N:8]1[CH2:13][CH2:12][C:11](=[CH:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([O:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=3)[CH:16]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[F:28][C:29]([F:34])([F:33])[C:30]([OH:32])=[O:31]>ClCCl>[F:28][C:29]([F:34])([F:33])[C:30]([OH:32])=[O:31].[NH:8]1[CH2:13][CH2:12][C:11](=[CH:14][C:15]2[CH:16]=[C:17]([CH:18]=[CH:19][CH:20]=2)[O:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=2)[CH2:10][CH2:9]1

참가 물질

4

반응물 2

HCID 6422Trifluoroacetic acidHCID 66875697HCID 66875697, 화합물

생성물 1

HCID 66875752HCID 66875752, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

A solution of tert-butyl-4-(3-(pyridin-2-yloxy)benzylidene)piperidine-1-carboxylate (0.483 g) in dichloromethane (2.5 mL, 0.53 M) was treated with trifluoroacetic acid (2.5 mL). The reaction was allowed to stir for 3 hours, then concentrated to give an oil. The oil was used without purification. 0.652 g, quantitative yield.

후처리

  1. concentrationconcentrated
  2. customto give an oil
  3. customThe oil was used without purification

출처 및 근거

ORD 기록
ord-9815bf5f1fed45d387b46bfb3130815d
출처 데이터셋
uspto-grants-2011_10
특허 번호
US08044052B2

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