Bactroban → Mupirocin Calcium

HRID 16668

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HRID 16668 반응식
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참가 물질

3

반응물 1

HCID 6435927Bactroban2회

생성물 1

HCID 5282317Mupirocin Calcium

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
5 °C

실험 절차

Amorphous mupirocin calcium (20.00 g, 19.20 mmole) was added into water (20 ml) under stirring. The slurry was stirred for 0.5 hour, and then it was cooled to 5° C. The mupirocin calcium solution was allowed to crystallize for 16 h. The crystal slurry was diluted with 15 ml water, and the crystals were filtered and washed with water (5 ml). The product (17.1 g) was dried at 35° C. for 12 h.

후처리

  1. stirringThe slurry was stirred for 0.5 hour
  2. customto crystallize for 16 h
  3. additionThe crystal slurry was diluted with 15 ml water
  4. filtrationthe crystals were filtered
  5. washwashed with water (5 ml)
  6. dry with materialThe product (17.1 g) was dried at 35° C. for 12 h.

출처 및 근거

ORD 기록
ord-c603df2915db4aa49e683e2e9f3cc60b
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07737177B2

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