5-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinoline → 2-Cyclopropyl-7-(3-{[4-methyl-5-(2-methyl-5-quinolinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine hydrochloride
반응식
[CH:1]1([C:4]2[O:5][C:6]3[C:16]([N:17]=2)=[CH:15][C:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14][C:8]=2[CH:7]=3)[CH2:3][CH2:2]1.[Cl:18][CH2:19][CH2:20][CH2:21][S:22][C:23]1[N:24]([CH3:39])[C:25]([C:28]2[CH:37]=[CH:36][CH:35]=[C:34]3[C:29]=2[CH:30]=[CH:31][C:32]([CH3:38])=[N:33]3)=[N:26][N:27]=1>>[ClH:18].[CH:1]1([C:4]2[O:5][C:6]3[C:16]([N:17]=2)=[CH:15][C:9]2[CH2:10][CH2:11][N:12]([CH2:19][CH2:20][CH2:21][S:22][C:23]4[N:24]([CH3:39])[C:25]([C:28]5[CH:37]=[CH:36][CH:35]=[C:34]6[C:29]=5[CH:30]=[CH:31][C:32]([CH3:38])=[N:33]6)=[N:26][N:27]=4)[CH2:13][CH2:14][C:8]=2[CH:7]=3)[CH2:3][CH2:2]1참가 물질
3
반응물 2
생성물 1
실험 절차
The title compound was prepared in analogy to General Procedure 1 from 2-cyclopropyl-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine (0.46 mmol) and 5-{5-[(3 chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl}-2-methylquinoline (0.544 mmol) and was obtained as a yellow solid (0.19 mmol).