2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-amine → N2-(2,2-Dimethyl-2,3-dihydro-benzofuran-7-yl)-N5-(1,1-dioxo-hexahydro-1lambda6-thiopyran-4-yl)-quinoline-2,5-diamine
반응식
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2I)[N:3]=1.[NH2:13][C:14]1[C:22]2[O:21][C:20]([CH3:24])([CH3:23])[CH2:19][C:18]=2[CH:17]=[CH:16][CH:15]=1.[O:25]=[S:26]1(=[O:33])[CH2:31][CH2:30][CH:29]([NH2:32])[CH2:28][CH2:27]1>>[CH3:23][C:20]1([CH3:24])[CH2:19][C:18]2[CH:17]=[CH:16][CH:15]=[C:14]([NH:13][C:2]3[CH:11]=[CH:10][C:9]4[C:8]([NH:32][CH:29]5[CH2:30][CH2:31][S:26](=[O:33])(=[O:25])[CH2:27][CH2:28]5)=[CH:7][CH:6]=[CH:5][C:4]=4[N:3]=3)[C:22]=2[O:21]1참가 물질
4
실험 절차
The title compound, MS: m/e=438.3 (M+H+), was prepared in accordance with the general method of example 3 from 2-chloro-5-iodo-quinoline (CAS 455955-26-7), 7-amino-2,3-dihydro-2,2-dimethylbenzofuran (CAS 68298-46-4) and 1,1-dioxo-tetrahydro-2H-thiopyran-4-amine.