참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dibenzofuran | HCID 568 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | Bromine | HCID 24408 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2-Bromodibenzofuran | HCID 6856 | 13% |
반응 단계
Bromine (23.8 g, 0.156 mol) in acetic acid (5 g) is added at 50° C. to a solution of dibenzofuran (25 g, 0.149 mol) in acetic acid (230 g). The mixture is then stirred at 50° C. for 4 hours. The reaction mixture is cooled to room temperature and poured into H2O. The orange solid is washed with Na2S2O3 aq. and H2O. The crude product is then purified by recrystallization from toluene/CH2Cl2, wherein the pure product is obtained as a white solid (13% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07989644B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_08 |
|---|
| ORD ID | ord-261dee3d83cf4f0a86d5560a33189962 |
|---|
| 출처 메모 | uspto-grants-2011_08 |
|---|
