Tetrahydro-4H-pyran-4-ol → (2,5-Dichloro-pyrimidin-4-yl)-[2-fluoro-6-(tetrahydro-pyran-4-yloxy)-phenyl]-amine

HRID 167222

반응식

HRID 167222 반응식
[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:17])[c:6]([NH:8][c:9]2[c:10]([OH:16])[cH:11][cH:12][cH:13][c:14]2[F:15])[n:7]1.[O:18]1[CH2:19][CH2:20][CH:21]([OH:24])[CH2:22][CH2:23]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:17])[c:6]([NH:8][c:9]2[c:10]([O:16][CH:21]3[CH2:20][CH2:19][O:18][CH2:23][CH2:22]3)[cH:11][cH:12][cH:13][c:14]2[F:15])[n:7]1

참가 물질

3

반응물 2

HCID 74956Tetrahydro-4H-pyran-4-olHCID 866339952-(2,5-Dichloro-pyrimidin-4-ylamino)-3-fluoro-phenol

생성물 1

HCID 86634000(2,5-Dichloro-pyrimidin-4-yl)-[2-fluoro-6-(tetrahydro-pyran-4-yloxy)-phenyl]-amine

출처 및 근거

ORD 기록
ord-8c7b92aa36a9466a866654040dc3bee3
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

연결된 노트

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