Trifluoroacetic acid → 2-(Benzamido)-4-(2,4-dichlorophenoxy)benzoic acid

참여 물질

반응 단계

5.0 mL of trifluoroacetic acid was added to the obtained tert-butyl 2-(benzamido)-4-(2,4-dichlorophenoxy)benzoate and stirred at room temperature for 2 hours. The solvent was evaporated under reduced pressure and the obtained residue was purified with reversed-phase silica gel column chromatography [eluent; 80-100% acetonitrile/0.1% trifluoroacetic acid aqueous solution] to obtain 8.7 mg of 2-(benzamido)-4-(2,4-dichlorophenoxy)benzoic acid as white solid.

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