Ethylamine → Ethyl-(3-methyl-isoxazol-5-ylmethyl)-amine

HRID 1674657노트

반응식

HRID 1674657 반응식
Cl[CH2:2][C:3]1[O:7][N:6]=[C:5]([CH3:8])[CH:4]=1.[CH2:9]([NH2:11])[CH3:10]>C1COCC1>[CH2:9]([NH:11][CH2:2][C:3]1[O:7][N:6]=[C:5]([CH3:8])[CH:4]=1)[CH3:10]

참가 물질

4

반응물 2

HCID 6341EthylamineHCID 71314965-(Chloromethyl)-3-methyl-1,2-oxazole

생성물 1

HCID 57511318Ethyl-(3-methyl-isoxazol-5-ylmethyl)-amine

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

prepared by reaction of 5-chloromethyl-3-methyl-isoxazole (Li W.-T. et al J. Med. Chem. 2003, 46, 9, 1706-1715) with 2M ethylamine in THF.

출처 및 근거

ORD 기록
ord-4e21e1ccb64440da9d1c86fdc177e539
출처 데이터셋
uspto-grants-2011_08
특허 번호
US08003654B2

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