4-[(Piperazin-1-yl)methyl]benzonitrile → 4-((4-(8-Methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperazin-1-yl)methyl)benzonitrile
반응식
[C:1]([C:3]1[CH:15]=[CH:14][C:6]([CH2:7][N:8]2[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]2)=[CH:5][CH:4]=1)#[N:2].Cl[C:17]1[CH:18]=[C:19]([CH3:30])[C:20]2[N:21]([C:23]([C:26]([F:29])([F:28])[F:27])=[N:24][N:25]=2)[N:22]=1>C(O)C>[CH3:30][C:19]1[C:20]2[N:21]([C:23]([C:26]([F:29])([F:27])[F:28])=[N:24][N:25]=2)[N:22]=[C:17]([N:11]2[CH2:12][CH2:13][N:8]([CH2:7][C:6]3[CH:5]=[CH:4][C:3]([C:1]#[N:2])=[CH:15][CH:14]=3)[CH2:9][CH2:10]2)[CH:18]=1참가 물질
4
반응 조건
- 온도
- 70 °C