반응식
[F:1][C:2]([F:29])([F:28])[C:3]1[CH:27]=[CH:26][CH:25]=[CH:24][C:4]=1[C:5]([N:7]1[CH2:11][C:10]2[CH2:12][N:13]([C:15]3[CH:23]=[CH:22][C:18]([C:19](O)=[O:20])=[CH:17][N:16]=3)[CH2:14][C:9]=2[CH2:8]1)=[O:6].[CH2:30]([NH2:35])[CH2:31][CH:32]([CH3:34])[CH3:33]>>[CH3:33][CH:32]([CH3:34])[CH2:31][CH2:30][NH:35][C:19](=[O:20])[C:18]1[CH:22]=[CH:23][C:15]([N:13]2[CH2:12][C:10]3[CH2:11][N:7]([C:5](=[O:6])[C:4]4[CH:24]=[CH:25][CH:26]=[CH:27][C:3]=4[C:2]([F:1])([F:29])[F:28])[CH2:8][C:9]=3[CH2:14]2)=[N:16][CH:17]=1참가 물질
3
실험 절차
6-[5-(2-Trifluoromethylbenzoyl)-3,4,5,6-tetrahydro-1H-pyrrolo[3,4-c]pyrrol-2-yl]nicotinic acid (40 mg, 0.099 mmol) was reacted with isoamylamine analogously to example 3d. Yield: 34%, M+H+: 473.18.
출처 및 근거
- ORD 기록
- ord-a948f7a0d71545b0a555405c031e6567
- 출처 데이터셋
- uspto-grants-2011_08
- 특허 번호
- US08003677B2
연결된 노트
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