N-(6-acetyl-3-methoxy-2-methylphenyl)-4-(trifluoromethyl)-1,3-thiazole-2-carboxamide → HCID 178487696, 화합물

반응식

[C:1]([C:4]1[C:9]([NH:10][C:11]([C:13]2[S:14][CH:15]=[C:16]([C:18]([F:21])([F:20])[F:19])[N:17]=2)=O)=[C:8]([CH3:22])[C:7]([O:23][CH3:24])=[CH:6][CH:5]=1)(=[O:3])[CH3:2].C(C1N=C(C2C=C(O)C3C(=CC(OC)=CC=3)N=2)SC=1)(C)C>>[CH3:24][O:23][C:7]1[C:8]([CH3:22])=[C:9]2[C:4]([C:1]([OH:3])=[CH:2][C:11]([C:13]3[S:14][CH:15]=[C:16]([C:18]([F:21])([F:20])[F:19])[N:17]=3)=[N:10]2)=[CH:5][CH:6]=1

참가 물질

반응물 2

HCID 56605151N-(6-acetyl-3-methoxy-2-methylphenyl)-4-(trifluoromethyl)-1,3-thiazole-2-carboxamide

HCID 178487691HCID 178487691, 화합물

생성물 1

HCID 178487696HCID 178487696, 화합물수율 73%

실험 절차

Compound 65b was synthesized from compound 64b as a yellow powder in 73% yield, following the procedure as described for compound 43a. MS (ESI, EI+) m/z=341 (MH+).

출처 및 근거

ORD 기록: ord-49f018874c754232bdea88d6064d906c
출처 데이터셋: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08003659B2

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