Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Toluene → 3,5-Difluoro-4-(2-propynyloxy)benzoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Toluene | HCID 1140 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 3,5-Difluoro-4-(2-propynyloxy)benzoic acid | HCID 57445666 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3,5-Difluoro-4-(2-propynyloxy)benzoyl chloride | HCID 57445696 | — |
반응 단계
To 17 ml of toluene were added 1.8 g of 3,5-difluoro-4-(2-propynyloxy)benzoic acid, 1 ml of thionyl chloride and 10 mg of DMF, and the resulting mixture was heated to reflux for 4 hours. Thereafter, the reaction mixture which had been allowed to cool to near room temperature was concentrated under reduced pressure, and 1.9 g of 3,5-difluoro-4-(2-propynyloxy)benzoyl chloride was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08003699B2 |
| 출처 데이터셋 | uspto-grants-2011_08 |
| ORD ID | ord-e11feb2091de4fb0a8761b24f77eb2ec |
| 출처 메모 | uspto-grants-2011_08 |