5-Fluoro-2-methoxythiophenol → 3-Chloro-4-[(5-fluoro-2-methoxyphenyl)thio]phenyl methyl sulfone

반응식

[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:9][CH3:10])=[C:6]([SH:8])[CH:7]=1.[CH3:11][S:12]([C:15]1[CH:20]=[CH:19][C:18](F)=[C:17]([Cl:22])[CH:16]=1)(=[O:14])=[O:13]>>[CH3:11][S:12]([C:15]1[CH:20]=[CH:19][C:18]([S:8][C:6]2[CH:7]=[C:2]([F:1])[CH:3]=[CH:4][C:5]=2[O:9][CH3:10])=[C:17]([Cl:22])[CH:16]=1)(=[O:14])=[O:13]

참가 물질

반응물 2

HCID 27590085-Fluoro-2-methoxythiophenol

HCID 213408802-Chloro-1-fluoro-4-methylsulfonylbenzene

생성물 1

HCID 669957343-Chloro-4-[(5-fluoro-2-methoxyphenyl)thio]phenyl methyl sulfone

실험 절차

The subtitle compound was prepared by the method of example 1 step (ii) using the product from step (ii) and the product from example 7 step (ii), yield 0.8 g.

출처 및 근거

ORD 기록: ord-692b418472204aca95c0541854e8add4
출처 데이터셋: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08003703B2

반응 노트

불러오는 중…