Piperidine-1-propylamine → HCID 67179342, 화합물

반응식

F[C:2]1[CH:7]=[CH:6][C:5]([C:8]([N:10]2[CH2:14][CH2:13][CH2:12][CH:11]2[CH2:15][N:16]2[CH2:20][CH2:19][CH2:18][CH2:17]2)=[O:9])=[CH:4][CH:3]=1.[N:21]1([CH2:27][CH2:28][CH2:29][NH2:30])[CH2:26][CH2:25]C[CH2:23][CH2:22]1>>[CH2:22]([N:21]([CH2:26][CH3:25])[CH2:27][CH2:28][CH2:29][NH:30][C:2]1[CH:7]=[CH:6][C:5]([C:8]([N:10]2[CH2:14][CH2:13][CH2:12][C@H:11]2[CH2:15][N:16]2[CH2:20][CH2:19][CH2:18][CH2:17]2)=[O:9])=[CH:4][CH:3]=1)[CH3:23]

참가 물질

반응물 2

HCID 19049Piperidine-1-propylamine

HCID 11964810(4-Fluoro-phenyl)-(2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone

생성물 1

HCID 67179342HCID 67179342, 화합물

실험 절차

(S)-[4-(3-Diethylamino-propylamino)-phenyl]-(2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone is prepared from (4-Fluoro-phenyl)-(2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone and 3-piperidino propylamine in a manner substantially similar to Procedure A. MS (APCI+) 399 (M+H)+.

출처 및 근거

ORD 기록: ord-448b74cac4344d4e994b873b314431db
출처 데이터셋: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08008296B2

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