2-Ethoxy-5-(trifluoromethyl)aniline → HCID 67329712, 화합물

반응식

[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]([F:13])([F:12])[F:11])=[CH:6][C:5]=1[NH2:14])[CH3:2].[N:15]([C:18]1[CH:23]=[CH:22][C:21]([B:24]2[O:28][C:27]([CH3:30])([CH3:29])[C:26]([CH3:32])([CH3:31])[O:25]2)=[CH:20][CH:19]=1)=[C:16]=[O:17].COC1C=C(C(F)(F)F)C=CC=1NC(NC1C=CC(B2OC(C)(C)C(C)(C)O2)=CC=1)=O>>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]([F:11])([F:13])[F:12])=[CH:6][C:5]=1[NH:14][C:16]([NH:15][C:18]1[CH:19]=[CH:20][C:21]([B:24]2[O:28][C:27]([CH3:30])([CH3:29])[C:26]([CH3:32])([CH3:31])[O:25]2)=[CH:22][CH:23]=1)=[O:17])[CH3:2]

참가 물질

반응물 3

HCID 12493272-Ethoxy-5-(trifluoromethyl)aniline

HCID 27734742-(4-Isocyanatophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

HCID 673294371-(2-Methoxy-4-trifluoromethylphenyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea

생성물 1

HCID 67329712HCID 67329712, 화합물

실험 절차

2-Ethoxy-5-trifluoromethylphenylamine is reacted with 2-(4-isocyanatophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane according to the preparation of 1-(2-methoxy-4-trifluoromethylphenyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea described in Example 5. After purification, a beige-coloured powder of 1-(2-ethoxy-5-trifluoromethylphenyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea is obtained, the characteristics of which are as follows: