Trifluoroacetic acid → HCID 58629078, 화합물

HRID 1678072노트

반응식

HRID 1678072 반응식
FC(F)(F)C(O)=O.[O:8]=[C:9]([CH3:28])[CH2:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([CH2:18][CH2:19][NH:20]C(=O)OC(C)(C)C)=[CH:14][CH:13]=1>C(Cl)Cl>[NH2:20][CH2:19][CH2:18][C:15]1[CH:16]=[CH:17][C:12]([O:11][CH2:10][C:9]([CH3:28])=[O:8])=[CH:13][CH:14]=1

참가 물질

4

반응물 2

HCID 6422Trifluoroacetic acidHCID 67310057Tert-butyl 2-[4-(2-oxopropoxy)phenyl]ethylcarbamate

생성물 1

HCID 58629078HCID 58629078, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Step 2 Trifluoroacetic acid (0.56 mL, 7.3 mmol) was added to a solution of tert-butyl 2-[4-(2-oxopropoxy)phenyl]ethylcarbamate (216 mg, 0.74 mmol) in CH2Cl2 (4 mL). The reaction mixture was stirred for 3 hr at ambient temperature, and then reaction mixture was stripped of volatiles in vacuo. The residue (143 mg) was used without further purification.

후처리

  1. customreaction mixture
  2. customThe residue (143 mg) was used without further purification

출처 및 근거

ORD 기록
ord-54d63711d7c34320824bf4bbf16b9e8e
출처 데이터셋
uspto-grants-2011_08
특허 번호
US08008487B2

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