Piperazine → HCID 11461092, 화합물

HRID 1678127노트

반응식

Cl[C:2]1[N:3]([C:13]2[CH:17]=[CH:16][S:15][CH:14]=2)[C:4]2[C:9]([C:10]=1[CH:11]=[O:12])=[CH:8][CH:7]=[CH:6][CH:5]=2.[NH:18]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1>>[N:18]1([C:2]2[N:3]([C:13]3[CH:17]=[CH:16][S:15][CH:14]=3)[C:4]3[C:9]([C:10]=2[CH:11]=[O:12])=[CH:8][CH:7]=[CH:6][CH:5]=3)[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1

참가 물질

반응물 2

HCID 4837Piperazine

HCID 86035948HCID 86035948, 화합물

생성물 1

HCID 11461092HCID 11461092, 화합물수율 78%

실험 절차

2-Chloro-1-(thien-3-yl)-1H-indole-3-carboxaldehyde as prepared above is reacted with piperazine as described in Example 3 to give the title compound as a pale yellow solid (78% yield). MS 409 (M+H)

출처 및 근거

ORD 기록: ord-257a54eb444d4bf48c12892dd8a3a672
출처 데이터셋: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08008491B2

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