Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonium Chloride → 4-Amino-7-(trifluoromethyl)quinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonium Chloride | HCID 25517 | — |
| 반응물 | 4-Chloro-7-(trifluoromethyl)quinoline | HCID 67668 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4-Amino-7-(trifluoromethyl)quinoline | HCID 2735960 | — |
반응 단계
A solution of 4-chloro-7-trifluoromethylquinoline (1 g) and ammonium chloride (1 g) in methanol (10 mL) was heated at 70° C. overnight. Then the solid was filtered off and washed with methanol. The filtrated was evaporated to give 4-amino-7-trifluoromethylquinoline. LCMS: ret. time: 14.81 min.; purity: 82.25%; MS (m/e): 228.11 (M+16).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08008501B2 |
| 출처 데이터셋 | uspto-grants-2011_08 |
| ORD ID | ord-2299b1780c344cf68e6af34e073ce4f6 |
| 출처 메모 | uspto-grants-2011_08 |