3-Nitro-4-(trifluoromethoxy)benzoic acid → 3-Amino-4-(trifluoromethoxy)benzoic acid
반응식
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[O:13][C:14]([F:17])([F:16])[F:15])[C:7]([OH:9])=[O:8])([O-])=O>CO>[NH2:1][C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[O:13][C:14]([F:15])([F:16])[F:17])[C:7]([OH:9])=[O:8]참가 물질
3
실험 절차
A solution of 3-nitro-4-trifluoromethoxybenzoic acid (3 g) in methanol (240 ml) was hydrogenated at 50° C. and 50 bar using H-cube apparatus. The methanol solution was evaporated giving the title compound as a white solid (2.58 g).
후처리
- customwas hydrogenated at 50° C.
- customThe methanol solution was evaporated
출처 및 근거
- ORD 기록
- ord-ebfd23b88677408e80c4208b95b8ebd6
- 출처 데이터셋
- uspto-grants-2011_08
- 특허 번호
- US08008303B2
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