Ethyl alpha-acetyl-4-methoxybenzenepropanoate → HCID 20361957, 화합물

HRID 1679761노트

반응식

HRID 1679761 반응식
C(O[C:4](=[O:18])[CH:5]([CH2:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=1)[C:6]([CH3:8])=O)C.[CH3:19][CH:20]([NH:28][NH2:29])[C:21]1[CH:26]=[CH:25][C:24]([CH3:27])=[CH:23][CH:22]=1>C(O)C>[CH3:8][C:6]1[NH:29][N:28]([CH:20]([CH3:19])[C:21]2[CH:26]=[CH:25][C:24]([CH3:27])=[CH:23][CH:22]=2)[C:4](=[O:18])[C:5]=1[CH2:9][C:10]1[CH:11]=[CH:12][C:13]([O:16][CH3:17])=[CH:14][CH:15]=1

참가 물질

4

반응물 2

HCID 12248936Ethyl alpha-acetyl-4-methoxybenzenepropanoateHCID 12489385HCID 12489385, 화합물

생성물 1

HCID 20361957HCID 20361957, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

31 g of α-(4-methoxybenzyl)-acetoacetic acid ethyl ester were added to a solution of 15 g of α-methyl-4-methylbenzylhydrazine in 30 ml of absolute ethanol in an inert gas atmosphere, during which the temperature of the reaction mixture rose to 60° C. After heating for 2 hours under reflux and standing overnight, the product crystallized out and was recrystallized from a mixture of ethanol and a little dimethylformamide.

후처리

  1. customrose to 60° C
  2. temperatureAfter heating for 2 hours
  3. temperatureunder reflux
  4. customthe product crystallized out
  5. customwas recrystallized from a mixture of ethanol

출처 및 근거

ORD 기록
ord-e8934a8c210548dc9955469bbf8e838f
출처 데이터셋
uspto-grants-1978_03
특허 번호
US04081596

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