Water → 2,3,4,9-Tetrahydro-6-methoxy-1H-carbazol-1-one

HRID 1679824노트

반응식

HRID 1679824 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9]N=C2CCCCC2=O)=[CH:5][CH:4]=1.[OH2:18].S(=O)(=O)(O)O>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:6](=[CH:7][CH:8]=1)[NH:9][C:4]1[C:5](=[O:18])[CH2:6][CH2:7][CH2:8][C:3]2=1

참가 물질

5

반응물 3

HCID 962WaterHCID 1118Sulfuric AcidHCID 753926HCID 753926, 화합물

생성물 1

HCID 28568112,3,4,9-Tetrahydro-6-methoxy-1H-carbazol-1-one

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

232 g. (1 mole) of cyclohexanedione-mono-p-methoxyphenylhydrazone, 1200 ml. of water, 350 g. of sulfuric acid (65 Be) and 100 ml. of ethanol are allowed to boil under reflux for three hours. After cooling down, the mixture is filtered with suction and rendered free from acid by washing with water. The resultant 6-methoxy-1,2,3,4-tetrahydrocarbazol-1-one melts at 222° C. and gives a yield of 193 g. (=90% of the theoretical).

후처리

  1. temperatureunder reflux for three hours
  2. temperatureAfter cooling down
  3. filtrationthe mixture is filtered with suction
  4. washby washing with water

출처 및 근거

ORD 기록
ord-c8c3d8b5a40a47e1b2c19341d86dfc4c
출처 데이터셋
uspto-grants-1981_06
특허 번호
US04271073

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