Sulfuric Acid → HCID 23457236, 화합물

HRID 1680168노트

반응식

HRID 1680168 반응식
[Cl:1][C:2]1[CH:16]=[CH:15][CH:14]=[C:13]([Cl:17])[C:3]=1[NH:4][C:5]1[C:6]([CH2:10][C:11]#[N:12])=[CH:7][S:8][CH:9]=1.S(=O)(=O)(O)[OH:19]>>[Cl:1][C:2]1[CH:16]=[CH:15][CH:14]=[C:13]([Cl:17])[C:3]=1[NH:4][C:5]1[C:6]([CH2:10][C:11]([NH2:12])=[O:19])=[CH:7][S:8][CH:9]=1

참가 물질

3

반응물 2

HCID 1118Sulfuric AcidHCID 23457191HCID 23457191, 화합물

생성물 1

HCID 23457236HCID 23457236, 화합물

실험 절차

28.3 g (0.1 mole) of 4-(2,6-dichloroanilino)-3-thiophenacetonitrile are introduced into 150 ml of concentrated sulfuric acid and stirred for one hour at room temperature. It is poured onto ice, and the precipitate which has formed is filtered off. Recrystallization from ethyl acetate yields 4-(2,6-dichloroanilino)-3-thiophenacetamide (m. 172° to 173°).

후처리

  1. additionIt is poured onto ice
  2. customthe precipitate which has formed
  3. filtrationis filtered off
  4. customRecrystallization from ethyl acetate

출처 및 근거

ORD 기록
ord-b9379a39fe8b4647abdcb1855130d5cb
출처 데이터셋
uspto-grants-1981_06
특허 번호
US04272507

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