Diethyl Ether → HCID 12898552, 화합물

HRID 1680259노트

반응식

[F:1][C:2]([F:22])([F:21])[C:3]([C:9]1[CH:18]=[C:17]([CH3:19])[C:12]([O:13][CH2:14][C:15]#[N:16])=[C:11]([CH3:20])[CH:10]=1)([OH:8])[C:4]([F:7])([F:6])[F:5].CC[O:25]CC>>[F:1][C:2]([F:21])([F:22])[C:3]([C:9]1[CH:18]=[C:17]([CH3:19])[C:12]([O:13][CH2:14][C:15]([NH2:16])=[O:25])=[C:11]([CH3:20])[CH:10]=1)([OH:8])[C:4]([F:6])([F:5])[F:7]

참가 물질

반응물 2

HCID 3283Diethyl Ether

HCID 54204577HCID 54204577, 화합물

생성물 1

HCID 12898552HCID 12898552, 화합물

실험 절차

Stir a sample of crude 2-[4-(hexafluoro-2-hydroxy-2-propyl)-2,6-dimethylphenoxy]acetonitrile, prepared as described in Example 8a, with ether for 30 minutes. Filter the solid and recrystallize from ether to obtain as a white solid, 2-[4-(hexafluoro-2-hydroxy-2-propyl)-2,6-dimethylphenoxy]acetamide, m.p. 180°-182° C.

후처리

customprepared
filtrationFilter the solid
customrecrystallize from ether

출처 및 근거

ORD 기록: ord-2beaa5c23df242cc9d83763625118722
출처 데이터셋: uspto-grants-1981_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04272550

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