Sulfur trioxide → Difluoromalonyl fluoride

HRID 1680408

반응식

HRID 1680408 반응식
C[O:2][C:3](F)([F:10])[C:4]([F:9])([F:8])[C:5]([F:7])=[O:6].S(=O)(=O)=O>>[F:8][C:4]([F:9])([C:5]([F:7])=[O:6])[C:3]([F:10])=[O:2]

참가 물질

3

반응물 2

HCID 24682Sulfur trioxideHCID 136846932,2,3,3-Tetrafluoro-3-methoxypropanoyl fluoride

생성물 1

HCID 2774099Difluoromalonyl fluoride

실험 절차

3-Methoxytetrafluoropropionyl fluoride (F. S. Fawcett, C. W. Tullock and D. D. Coffman, J. Amer. Chem. Soc., 84, 4275 (1962)) (81 g, 0.45 mol) was slowly added to sulfur trioxide (80 g, 1.0 mol) at 40° C., and the product difluoromalonyl difluoride, bp -9° C., was continuously removed by distillation through a low temperature still, yield 58 g (0.40 mol, 90%). The product structure was confirmed by: λmax 1860 cm-1 (COF), 19F NMR (no solvent), +17.1 ppm (t J=10 Hz) 2F, COF and -114.2 ppm (t J=10 Hz) 2F, CF2.

후처리

  1. customthe product difluoromalonyl difluoride, bp -9° C., was continuously removed by distillation through a low temperature still

출처 및 근거

ORD 기록
ord-e7060104b948402dbaf13a5afc904951
출처 데이터셋
uspto-grants-1981_06
특허 번호
US04273728

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