2-Methoxyethanol → Ethanamine, 2-(2-methoxyethoxy)-N,N-bis[2-(2-methoxyethoxy)ethyl]-

HRID 1680521

반응식

HRID 1680521 반응식
Cl.Cl[CH2:3][CH2:4][N:5]([CH2:9][CH2:10]Cl)[CH2:6][CH2:7]Cl.[CH3:12][O:13][CH2:14][CH2:15][OH:16]>>[CH2:4]([N:5]([CH2:9][CH2:10][O:16][CH2:15][CH2:14][O:13][CH3:12])[CH2:6][CH2:7][O:16][CH2:15][CH2:14][O:13][CH3:12])[CH2:3][O:16][CH2:15][CH2:14][O:13][CH3:12]

참가 물질

3

반응물 2

HCID 80192-MethoxyethanolHCID 61220Tris(2-chloroethyl)amine hydrochloride

생성물 1

HCID 112414Ethanamine, 2-(2-methoxyethoxy)-N,N-bis[2-(2-methoxyethoxy)ethyl]-

실험 절차

To the preceding mixture, 51.6 g tris-(2-chloroethyl)amine hydrochloride (0.215 mole) were added. The mixture was then heated under reflux of the 2-methoxyethanol (θ=125° C.) for 12 hours and the solvent distilled off under reduced pressure. The excess sodium 2-methoxyethanolate was neutralized by addition of 11.6 cm3 of aqueous (10 N) HCl. The sodium chloride was filtered and the solution distilled.

후처리

  1. temperatureThe mixture was then heated
  2. distillationthe solvent distilled off under reduced pressure
  3. additionThe excess sodium 2-methoxyethanolate was neutralized by addition of 11.6 cm3 of aqueous (10 N) HCl
  4. filtrationThe sodium chloride was filtered
  5. distillationthe solution distilled

출처 및 근거

ORD 기록
ord-562d5e4fb5c145b2b0f8736c0f8d05d9
출처 데이터셋
uspto-grants-1981_06
특허 번호
US04273915

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