[1,1'-Biphenyl]-3-carbonitrile → 2-[(1,1'-Biphenyl)-3-yl]-1,2,4-triazolo[5,1-a]isoquinoline

HRID 1680627

반응식

HRID 1680627 반응식
[NH2:1][N:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]1=O.[C:13]1([C:19]2[CH:20]=[C:21]([CH:24]=[CH:25][CH:26]=2)[C:22]#[N:23])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C(OCC)(=O)C>[C:19]1([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:26]=[CH:25][CH:24]=[C:21]([C:22]2[N:23]=[C:3]3[C:4]4[C:9]([CH:10]=[CH:11][N:2]3[N:1]=2)=[CH:8][CH:7]=[CH:6][CH:5]=4)[CH:20]=1

참가 물질

4

반응물 2

HCID 34340[1,1'-Biphenyl]-3-carbonitrileHCID 123832182-Amino-1(2H)-isoquinolinone

생성물 1

HCID 130210762-[(1,1'-Biphenyl)-3-yl]-1,2,4-triazolo[5,1-a]isoquinoline수율 49%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

This compound was prepared according to the procedure of the foregoing Example, starting from 2-amino-isoquinoline-1(2H)-one and 3-phenyl-benzonitrile. Yield 49%. M.p. 167°-69° C. (from ethyl acetate).

후처리

  1. customThis compound was prepared

출처 및 근거

ORD 기록
ord-81b9dc8f2612487f87071bbfe77c3da9
출처 데이터셋
uspto-grants-1981_06
특허 번호
US04275066

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