3-Aminopyrazine-2-carbonitrile → HCID 10543796, 화합물
반응식
[NH2:1][C:2]1[C:3]([C:8]#[N:9])=[N:4][CH:5]=[CH:6][N:7]=1.[Cl:10][C:11]1[CH:12]=[C:13]([CH:19]=[CH:20][C:21]=1[Cl:22])[O:14][CH2:15][C:16](N)=[NH:17].C(O)C.CN(C)C=O>C(O)C>[NH2:9][C:8]1[C:3]2[C:2](=[N:7][CH:6]=[CH:5][N:4]=2)[N:1]=[C:16]([CH2:15][O:14][C:13]2[CH:19]=[CH:20][C:21]([Cl:22])=[C:11]([Cl:10])[CH:12]=2)[N:17]=1참가 물질
5
실험 절차
Obtained using the procedure described in section c of Example 2, starting with 9.6 g (0.080 mole) of 3-amino-2-pyrazinecarbonitrile and 26.3 g (0.12 mole) of 2-(3,4-dichlorophenoxy)acetamidine in 520 ml of absolute ethanol. Refluxing time: 3 hours. Yld: 18.0 g (70%), m.p. 261°-263° C. (ethanol/N,N-dimethylformamide).
후처리
- customObtained
- temperatureRefluxing time
- custom3 hours
출처 및 근거
- ORD 기록
- ord-08cb5d313c9a491897a6431f12dff9c9
- 출처 데이터셋
- uspto-grants-1992_12
- 특허 번호
- US05167949
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