참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | (R,R)-Stilbene oxide | HCID 185583 | — |
| 반응물 | 2-(Benzyloxy)propan-1-amine | HCID 296015 | — |
| 생성물 | alpha-Phenyl-beta-[[2-(phenylmethoxy)propyl]amino]benzeneethanol | HCID 19806389 | 75.2% |
반응 단계
A mixture of trans-stilbene oxide (1.96 g, 0.010 mol) and 2-benzyloxypropylamine (2.48 g, 0.015 mol) was heated at 140° C. for 6 hours and then allowed to stand at ambient temperature for 12 hours. The solidified reaction mixture was triturated with petroleum ether and filtered to obtain 2.72 g of a solid. Mass spectral analysis showed starting materials present. Recrystallization from isooctane gave 2.16 g (60%) of the product as a white solid; mp 114°-119° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US05171753 |
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| 출처 데이터셋 | uspto-grants-1992_12 |
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| ORD ID | ord-439ae5a08b1241f3abeadb21b0bafc7d |
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| 출처 메모 | uspto-grants-1992_12 |
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