Methanol → 1-Cyclopropylpiperazine
반응식
Cl.Cl.[CH:3]1([N:6]2[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]2)[CH2:5][CH2:4]1.CO>O>[CH:3]1([N:6]2[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]2)[CH2:5][CH2:4]1참가 물질
4
실험 절차
1-Cyclopropylpiperazine dihydrochloride (1.493 g, 7.5 mmol) was dissolved in water (5.00 mL) and methanol (5.00 mL) and converted to its freebase by ion exchange chromatography, using an SCX column. The desired product was eluted from the column using 3.5M ammonia in methanol and pure fractions were evaporated to dryness to afford 1-cyclopropylpiperazine (0.796 g, 84%) as an oil.
후처리
- washThe desired product was eluted from the column
- customwere evaporated to dryness
출처 및 근거
- ORD 기록
- ord-52133c47f1534988bfc9e04dd961a467
- 출처 데이터셋
- uspto-grants-2010_06
- 특허 번호
- US07737149B2
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