3-Cyanopyridine → 4-[(3-Cyano-pyridin-2-ylamino)-methyl]-piperidine-1-carboxylic acid benzyl ester

반응식

[C:19](#[N:20])[c:21]1[cH:22][n:23][cH:24][cH:25][cH:26]1.[CH3:27][CH2:28][O:29][C:30]([CH3:31])=[O:32].[NH2:1][CH2:2][CH:3]1[CH2:4][CH2:5][N:6]([C:9](=[O:10])[O:11][CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:7][CH2:8]1>>[NH:1]([CH2:2][CH:3]1[CH2:4][CH2:5][N:6]([C:9](=[O:10])[O:11][CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:7][CH2:8]1)[c:22]1[c:21]([C:19]#[N:20])[cH:26][cH:25][cH:24][n:23]1

참가 물질

반응물 3

HCID 793-Cyanopyridine

HCID 8857Ethyl Acetate

HCID 219554994-Aminomethyl-1-N-Cbz-piperidine

생성물 1

HCID 99464084-[(3-Cyano-pyridin-2-ylamino)-methyl]-piperidine-1-carboxylic acid benzyl ester

출처 및 근거

ORD 기록: ord-699be1cd40704720a8219b215b11f61e
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…