6,7-Dimethyl-3,4-dihydroisoquinolin-1(2H)-one → HCID 19803626, 화합물

반응식

[CH3:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[CH3:12])[C:8](=[O:13])[NH:7][CH2:6][CH2:5]2.[Cl:14][CH2:15][CH:16]1[CH2:21][CH2:20][CH2:19][N:18]([CH2:22][CH2:23][CH2:24][C:25]2[CH:34]=[CH:33][C:32]3[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=3)[CH:26]=2)[CH2:17]1>>[ClH:14].[CH:26]1[C:27]2[C:32](=[CH:31][CH:30]=[CH:29][CH:28]=2)[CH:33]=[CH:34][C:25]=1[CH2:24][CH2:23][CH2:22][N:18]1[CH2:19][CH2:20][CH2:21][CH:16]([CH2:15][N:7]2[CH2:6][CH2:5][C:4]3[C:9](=[CH:10][C:11]([CH3:12])=[C:2]([CH3:1])[CH:3]=3)[C:8]2=[O:13])[CH2:17]1

참가 물질

반응물 2

HCID 178048946,7-Dimethyl-3,4-dihydroisoquinolin-1(2H)-one

HCID 19803679HCID 19803679, 화합물

생성물 1

HCID 19803626HCID 19803626, 화합물

실험 절차

Prepared from 6,7-dimethyl-1-oxo-1,2,3,4-tetrahydro-isoquinoline and 3-chloromethyl-N-[3-(naphth-2-yl)-propyl]-piperidine analogously to Example 2.

출처 및 근거

ORD 기록: ord-d7f8bf50d74a4eefbea85bf37a18e4a6
출처 데이터셋: uspto-grants-1992_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05175157

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