2,4-Dichloro-1-(4-chlorobutoxy)benzene → 2-[(N-(4-(2,4-Dichloro-phenoxy)-butyl)-piperidin-3-yl)-methyl]-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochloride
반응식
[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][N:8]2[CH2:17][CH2:16][C:15]3[C:10](=[CH:11][C:12]([O:20][CH3:21])=[C:13]([O:18][CH3:19])[CH:14]=3)[C:9]2=[O:22])[CH2:2]1.[Cl:23][CH2:24][CH2:25][CH2:26][CH2:27][O:28][C:29]1[CH:34]=[CH:33][C:32]([Cl:35])=[CH:31][C:30]=1[Cl:36]>>[ClH:23].[Cl:36][C:30]1[CH:31]=[C:32]([Cl:35])[CH:33]=[CH:34][C:29]=1[O:28][CH2:27][CH2:26][CH2:25][CH2:24][N:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][N:8]2[CH2:17][CH2:16][C:15]3[C:10](=[CH:11][C:12]([O:20][CH3:21])=[C:13]([O:18][CH3:19])[CH:14]=3)[C:9]2=[O:22])[CH2:2]1참가 물질
3
실험 절차
Prepared from 2-[(piperidin-3-yl)-methyl]-6,7-dimethyoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline and 1-chloro-4-(2,4-dichlorophenoxy)-butane analogously to Example 1.
출처 및 근거
- ORD 기록
- ord-971b011bddd643b09bc5ecb58f72f334
- 출처 데이터셋
- uspto-grants-1992_12