1-(3-Chloropropoxy)-3-methylbenzene → 2-[(N-(3-(3-Methyl-phenoxy)-propyl)-piperidin-3-yl)-methyl]-6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochloride

HRID 1682041노트

반응식

HRID 1682041 반응식
[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][N:8]2[CH2:17][CH2:16][C:15]3[C:10](=[CH:11][C:12]4[O:20][CH2:19][O:18][C:13]=4[CH:14]=3)[C:9]2=[O:21])[CH2:2]1.[CH3:22][C:23]1[CH:24]=[C:25]([CH:31]=[CH:32][CH:33]=1)[O:26][CH2:27][CH2:28][CH2:29][Cl:30]>>[ClH:30].[CH3:22][C:23]1[CH:24]=[C:25]([CH:31]=[CH:32][CH:33]=1)[O:26][CH2:27][CH2:28][CH2:29][N:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][N:8]2[CH2:17][CH2:16][C:15]3[C:10](=[CH:11][C:12]4[O:20][CH2:19][O:18][C:13]=4[CH:14]=3)[C:9]2=[O:21])[CH2:2]1

참가 물질

3

반응물 2

HCID 127603061-(3-Chloropropoxy)-3-methylbenzeneHCID 198037112-[(Piperidin-3-yl)-methyl]-6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline

생성물 1

HCID 198035622-[(N-(3-(3-Methyl-phenoxy)-propyl)-piperidin-3-yl)-methyl]-6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochloride

실험 절차

Prepared from 2-[(piperidin-3-yl)-methyl]-6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline and 3-(3-methyl-phenoxy)-1- chloro-propane analogously to Example 1.

출처 및 근거

ORD 기록
ord-436252afa1624f38a22e89941abb1e96
출처 데이터셋
uspto-grants-1992_12
특허 번호
US05175157

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