6,7-Dimethyl-3,4-dihydroisoquinolin-1(2H)-one → HCID 19803879, 화합물

반응식

[CH3:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[CH3:12])[C:8](=[O:13])[NH:7][CH2:6][CH2:5]2.[Cl:14][CH2:15][CH:16]1[CH2:20][CH2:19][N:18]([CH2:21][CH2:22][CH2:23][C:24]2[CH:29]=[CH:28][N:27]=[CH:26][CH:25]=2)[CH2:17]1>>[OH2:13].[ClH:14].[ClH:14].[N:27]1[CH:28]=[CH:29][C:24]([CH2:23][CH2:22][CH2:21][N:18]2[CH2:19][CH2:20][CH:16]([CH2:15][N:7]3[CH2:6][CH2:5][C:4]4[C:9](=[CH:10][C:11]([CH3:12])=[C:2]([CH3:1])[CH:3]=4)[C:8]3=[O:13])[CH2:17]2)=[CH:25][CH:26]=1

참가 물질

반응물 2

HCID 178048946,7-Dimethyl-3,4-dihydroisoquinolin-1(2H)-one

HCID 19803469HCID 19803469, 화합물

생성물 1

HCID 19803879HCID 19803879, 화합물

실험 절차

Prepared from 6,7-dimethyl-1-oxo-1,2,3,4-tetrahydro-isoquinoline and 3-chloromethyl-N-[3-(pyrid-4-yl)-propyl]-pyrrolidine analogously to Example 2.

출처 및 근거

ORD 기록: ord-2359e34e33a540aa98d51d24b63f613e
출처 데이터셋: uspto-grants-1992_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05175157

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