Noroxyhydrastinine → 2-[2-(N-(3-(Pyrid-4-yl)-propyl)-piperid-2-yl)-ethyl]-6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-dihydrochloride-dihydrate
반응식
[CH2:1]1[O:13][C:12]2[CH:11]=[C:10]3[C:5]([CH2:6][CH2:7][NH:8][C:9]3=[O:14])=[CH:4][C:3]=2[O:2]1.[Cl:15][CH2:16][CH2:17][CH:18]1[CH2:23][CH2:22][CH2:21][CH2:20][N:19]1[CH2:24][CH2:25][CH2:26][C:27]1[CH:32]=[CH:31][N:30]=[CH:29][CH:28]=1>>[OH2:2].[OH2:2].[ClH:15].[ClH:15].[N:30]1[CH:31]=[CH:32][C:27]([CH2:26][CH2:25][CH2:24][N:19]2[CH2:20][CH2:21][CH2:22][CH2:23][CH:18]2[CH2:17][CH2:16][N:8]2[CH2:7][CH2:6][C:5]3[C:10](=[CH:11][C:12]4[O:13][CH2:1][O:2][C:3]=4[CH:4]=3)[C:9]2=[O:14])=[CH:28][CH:29]=1참가 물질
3
실험 절차
Prepared from 6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline and 2-(2-chloroethyl)-N-[3-(pyrid-4-yl)-propyl]piperidine analogously to Example 2.
출처 및 근거
- ORD 기록
- ord-9b97195dead14d9c95b798f85109d486
- 출처 데이터셋
- uspto-grants-1992_12