1,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one → HCID 67917873, 화합물

반응식

[CH3:1][O:2][C:3]1[C:14]([O:15][CH3:16])=[CH:13][C:6]2[CH2:7][C:8](=[O:12])[NH:9][CH:10]=[CH:11][C:5]=2[CH:4]=1.Cl[CH2:18][CH:19]1[CH2:24][CH2:23][CH2:22][N:21]([CH2:25][CH2:26][C:27]2[C:36]3[C:31](=[CH:32][C:33]([O:39][CH3:40])=[C:34]([O:37][CH3:38])[CH:35]=3)[CH:30]=[N:29][CH:28]=2)[CH2:20]1>>[OH2:2].[CH3:38][O:37][C:34]1[CH:35]=[C:36]2[C:31](=[CH:32][C:33]=1[O:39][CH3:40])[CH:30]=[N:29][CH:28]=[C:27]2[CH2:26][CH2:25][N:21]1[CH2:22][CH2:23][CH2:24][CH:19]([CH2:18][N:9]2[C:8](=[O:12])[CH2:7][C:6]3[CH:13]=[C:14]([O:15][CH3:16])[C:3]([O:2][CH3:1])=[CH:4][C:5]=3[CH:11]=[CH:10]2)[CH2:20]1

참가 물질

반응물 2

HCID 14823731,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one

HCID 19803654HCID 19803654, 화합물

생성물 1

HCID 67917873HCID 67917873, 화합물

실험 절차

Prepared from 7,8-dimethoxy-2-oxo-1,3-dihydro-2H-3-benzazepine and 3-chloromethyl-N-[2-(6,7-dimethoxy-isoquinol-4-yl)-ethyl]piperidine analogously to Example 2.

출처 및 근거

ORD 기록: ord-3e401f83337d4f7b9270d3a2c8e9808b
출처 데이터셋: uspto-grants-1992_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05175157

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