7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one → 3-[(N-(2-(4-Methoxy-phenyl)-ethyl)-hexahydro-azepin-3-yl)methyl]-7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepinehydrochloride
반응식
[CH3:1][O:2][C:3]1[C:14]([O:15][CH3:16])=[CH:13][C:6]2[CH2:7][C:8](=[O:12])[NH:9][CH2:10][CH2:11][C:5]=2[CH:4]=1.[CH3:17][O:18][C:19]1[CH:24]=[CH:23][C:22]([CH2:25][CH2:26][N:27]2[CH2:33][CH2:32][CH2:31][CH2:30][CH:29]([CH2:34][Cl:35])[CH2:28]2)=[CH:21][CH:20]=1>>[ClH:35].[CH3:17][O:18][C:19]1[CH:20]=[CH:21][C:22]([CH2:25][CH2:26][N:27]2[CH2:33][CH2:32][CH2:31][CH2:30][CH:29]([CH2:34][N:9]3[C:8](=[O:12])[CH2:7][C:6]4[CH:13]=[C:14]([O:15][CH3:16])[C:3]([O:2][CH3:1])=[CH:4][C:5]=4[CH2:11][CH2:10]3)[CH2:28]2)=[CH:23][CH:24]=1참가 물질
3
실험 절차
Prepared from 7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepine and N-[2-(4-methoxy-phenyl)-ethyl]-3-chloromethylhexahydro-azepine analogously to Example 2.
출처 및 근거
- ORD 기록
- ord-91fa72f204394a3fa2e503865740eb36
- 출처 데이터셋
- uspto-grants-1992_12