Ammonia → 1-Tert-butoxycarbonyl-4-(pyridin-3-yl)-piperidine-4-carboxylic acid amide

HRID 1683004노트

반응식

HRID 1683004 반응식
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][C:11]([C:17]2[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=2)([C:14](O)=[O:15])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[NH3:23]>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][C:11]([C:17]2[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=2)([C:14]([NH2:23])=[O:15])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 222AmmoniaHCID 543822421-(tert-Butoxycarbonyl)-4-(pyridin-3-yl)piperidine-4-carboxylic acid

생성물 1

HCID 539785191-Tert-butoxycarbonyl-4-(pyridin-3-yl)-piperidine-4-carboxylic acid amide

실험 절차

Prepare by the method of example 20.8 using 1-tert-butoxycarbonyl-4-(pyridin-3-yl)-piperidine-4-carboxylic acid (4.0 mmol) and NH3 (gas). Purify to give the title compound.

후처리

  1. customPurify

출처 및 근거

ORD 기록
ord-0274340735c84d34940e6d54763197e5
출처 데이터셋
uspto-grants-1997_06
특허 번호
US05635510

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