HCID 53909159, 화합물 → 2-(Trimethylsilyl)ethyl 2-azido-2-deoxy-beta-D-galactopyranoside

HRID 1683156노트

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HRID 1683156 반응식
C([O:4][C@H:5]1[C@@H:17]([O:18]C(=O)C)[C@@H:16]([CH2:22][O:23]C(=O)C)[O:15][C@@H:7]([O:8][CH2:9][CH2:10][Si:11]([CH3:14])([CH3:13])[CH3:12])[C@@H:6]1[N:27]=[N+:28]=[N-:29])(=O)C>C[O-].[Na+]>[N:27]([C@@H:6]1[C@@H:5]([OH:4])[C@@H:17]([OH:18])[C@@H:16]([CH2:22][OH:23])[O:15][C@H:7]1[O:8][CH2:9][CH2:10][Si:11]([CH3:13])([CH3:14])[CH3:12])=[N+:28]=[N-:29]

참가 물질

3

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HCID 53909159HCID 53909159, 화합물

생성물 1

HCID 108597232-(Trimethylsilyl)ethyl 2-azido-2-deoxy-beta-D-galactopyranoside수율 94%

시약·촉매·용매 1

HCID 10942334Sodium Methoxide용매

실험 절차

Compound 23 (4.88 g, 11.3 mmol) was stirred in methanolic NaOMe (0.04M, 50 ml) for 90 min. The mixture was decationised with Amberlite IR-120(H+) resin, filtered and evaporated to dryness to give 24 (3.24 g, 94%), [α]D25 +8.5° (c 0.8, MeOH), m.p. 158°-161° C. (ether-heptane).

후처리

  1. filtrationfiltered
  2. customevaporated to dryness

출처 및 근거

ORD 기록
ord-7eff57a15f2e46a6a938e4b7527edaee
출처 데이터셋
uspto-grants-1997_06
특허 번호
US05637569

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