Boron tribromide → HCID 19040965, 화합물
반응식
C[O:2][C:3]1[CH:17]=[C:16]([O:18]C)[CH:15]=[CH:14][C:4]=1[C:5]([N:7]([CH:11]([CH3:13])[CH3:12])[CH:8]([CH3:10])[CH3:9])=[O:6].B(Br)(Br)Br>ClCCl>[OH:2][C:3]1[CH:17]=[C:16]([OH:18])[CH:15]=[CH:14][C:4]=1[C:5]([N:7]([CH:11]([CH3:12])[CH3:13])[CH:8]([CH3:9])[CH3:10])=[O:6]참가 물질
4
실험 절차
A solution of 2,4-dimethoxy-N,N-bis(1-methylethyl)benzamide (3.0 g, 11.0 mmol) in 10 ml of dichloromethane at 0° C. is treated with 1N boron tribromide (33.0 mL, 33.0 mmol) and stirred at room temperature for 2 hours. The reaction is concentrated in vacuo, dissolved in 1N sodium hydroxide solution, and acidified with 1N hydrochloric acid to generate solid which is filtered to afford 2,4-dihydroxy-N,N-bis(1-methylethyl)benzamide as white solid.
후처리
- concentrationThe reaction is concentrated in vacuo
- dissolutiondissolved in 1N sodium hydroxide solution
- filtrationis filtered
출처 및 근거
- ORD 기록
- ord-38661e6e5c8349afb4df93eb2fbdd7e8
- 출처 데이터셋
- uspto-grants-1997_06
- 특허 번호
- US05639768
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