Pyridine → 4-{[2-(3,5-Difluoro-phenyl)-acetylamino]-methyl}-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester

HRID 168423

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[cH:15][cH:16][c:17]([I:20])[cH:18][cH:19]2)([CH2:21][NH2:22])[CH2:12][CH2:13]1.[CH3:44][CH2:45][O:46][C:47]([CH3:48])=[O:49].[Cl:41][CH2:42][Cl:43].[F:23][c:24]1[cH:25][c:26]([CH2:31][C:32](=[O:33])[Cl:34])[cH:27][c:28]([F:30])[cH:29]1.[cH:35]1[cH:36][cH:37][n:38][cH:39][cH:40]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[cH:15][cH:16][c:17]([I:20])[cH:18][cH:19]2)([CH2:21][NH:22][C:32]([CH2:31][c:26]2[cH:25][c:24]([F:23])[cH:29][c:28]([F:30])[cH:27]2)=[O:33])[CH2:12][CH2:13]1